3DT (Drugs and Devices for Diagnostics and Therapeutics) Holdings, LLC is a San Diego based incubator/accelerator with expertise in pathology core, bench studies computational modeling and simulations, and operating a clinical research laboratory (CRL). It also collaborates with The California Medical Innovations Institute (CalMI2) and shares a common founder (Dr. Ghassan S Kassab). Cal-MI2 is a San Diego-based, non-profit, independent research institute focusing on basic research in the cardiovascular and metabolic disease space. 3DT collaborates with CalMI2, fostering a unique environment with a multidisciplinary and collaborative approach. Our multi-discipline (experimental and computational), multi-physics (fluid and solid mechanics, mass transport, electro-magnetic, etc.) and multi-scale (from molecule to cell to tissue to organ) methods provide a unique environment for testing safety and efficacy of medical devices, pharmaceuticals and biologics.

The USDA-approved, AAALAC accredited facilities including two sterile surgical suites, post surgical recovery rooms and radiology and diagnostic laboratories. The Institute has two C-arms (flat-panel) dedicated to research that requires the ability to visualize vasculature and internal organs with radiologic contrast for diagnostic procedures, therapy, and monitoring of surgical procedure efficacy. The equipment is a poly-diagnostic ‘C-arm’ configuration that allows both right and left anterior oblique views as well as the full range of simultaneous cranial and caudal views. Images are archived using fully digital capture in DICOM format for networking with human clinical cardiac catheterization labs for consultation with clinicians or sharing of images. The Institute is also equipped with IVUS as well as dual band and transesophageal ultrasound. Most importantly, the facility is available for physiological monitoring that requires relatively dedicated, extended durations. Based on its size, equipment and staff, the facility is ideal for facilitating the creation and physician training of new devices and approaches.

In addition, 3DT has access to various facilities and resources, through Sponsored Research Agreements and collaborations, at nearby Scripps and Salk Institutes, UC Irvine and UC San Diego, including the San Diego Super computer Center, and several research libraries.

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