The vision is to improve healthcare through innovations by partnering with industry, clinicians, and entrepreneurs to enhance quality of life for humankind.
Ghassan Kassab, Ph.D., Founder, Managing Member
Dr. Kassab received his BS (Chemical Engineering), MS (Engineering Sciences) and PhD (Bioengineering, Summa Cum Laude) from University of California, San Diego. He previously served as the Thomas J. Linnemeier Guidant Foundation Chair and Professor in Biomedical Engineering, Professor in Surgery, Cellular and Integrative Physiology at Indiana University Purdue University, Indianapolis. He is currently the Founder/President/CSO of California Medical Innovations Institute in San Diego.Dr. Kassab is the recipient of the NIH Young Investigator Award, the AHA Established Investigator Award, Farriborz Maseeh Best Research Award, Abraham M. Max Distinguished Professor Award, Eminent Engineer Award of Tau Beta Pi Engineering Honor Society, Indiana’s President Circle Award, and Glenn Irwin, MD Chancellor Best Research Scholar Award. He is also a Fellow of the American Institute for Medical and Biological Engineering, the American Physiological Society Cardiovascular Section and the American Venous Forum. He has servedas a regular reviewer on two NIH study sections (Systems Biology; and Hypertension and Microcirculation) and as ad hoc on multiple other study sections;the Editorial Board of American Journal of Physiology-Heart and Circulatory Physiology, Journal of Biomechanics, and has previously served as an Associate Editor of Mechanics and Chemistry of Biosystems. Dr. Kassab has published over 500proceedings, abstracts and full length publications and his current scientific interests encompass the biomechanics of cardiovascular and gastroenterology systems in health and disease. He also has over 250 issued or pending patents in the areas of diagnosis and treatment of heart failure (including electrical, valvular and coronary artery disease), aneurysm, and obesity. Dr. Kassab’s intellectual properties have resulted in multiple start-ups and exclusive licensesto medical device industry.
Brad Klos, Director of Business Development
Mr. Klos currently serves as the Vice President of Business Development at 3DT Holdings. He is also the CEO of CardioPathways a company launched out of 3DT and the President and Founder of Solana Medtech, a medical device consulting group specializing in commercialization and business development strategies for life science companies. Previously, he was the Senior Director of Market Development at Acutus Medical and Director of Global Marketing at Philips Healthcare for the Temperature Management Business Unit. Mr. Klos previously held the position of Vice President of Sales and Marketing at InnerCool Therapies. His background spans across a number of interventional device and surgical specialties where he gained experience in upstream & downstream marketing, sales management as well as clinical and business development. He holds both a BA in International Relations and MBA from the University of San Diego.
William Combs, Director of Engineering
Bill Combs has over 35 years of experience researching and implementing novel medical device therapies and diagnostics. Over a 29-year career at Medtronic, he held a wide range of positions relevant to implementation and commercialization of concepts and technologies including leadership positions in Systems Engineering, Product Planning and Research. Bill was a Medtronic Technical Fellow, holds 40 issued patents and was twice named Medtronic Technical Contributor of the Year. Bill has directly participated in the commercialization of impedance monitoring in implanted pacemakers and defibrillators, leading the Research team that investigated the applications and commercialization of accelerometer and impedance-based rate adaptive cardiac pacing and heart failure fluid status monitoring,He is a Clinical Associate Professor for the IUPUI School of Biomedical Engineering, graduated with a MSEE degree from Purdue University where he participated in research investigating cardiac defibrillation with indwelling lead and electrode systems. Bill is presently leading 3DT efforts to identify and implement novel technologies that will improve patient outcomes.
George Mansfield, Sr. Development Engineer/Project Manager
Mr. Mansfield brings 27 years of product development experience to 3DT. He has 18 years of experience developing medical devices, including catheters, electroporation devices, spinal implants and endoscopes, such as neuroendoscopes, angioscopes and ureteroscopes. He has also developed biotech instruments, radiation detection equipment and electromechanical devices. He developed the first device to automatically tattoo a permanent 3-digit ID on a mouse tail for animal studies. Mr. Mansfield has 11 issued U.S. patents and holds a B.S. in Mechanical Engineering from San Diego State University.
Terry Hubbard, Sr. Engineer/Project manager
Terry has been immersed in medical device design and commercialization for more than 30 years. At a number of large and startup companies, he has developed and brought to market a wide range of products including high volume peripheral infusion products, ventricular assist devices, soft tissue prothesis, artificial organs and microarray molecular assay devices. Terry has participated in FDA PMA submissions and has managed multi-site clinical research. He has extensive experience with implant and peripheral access technologies, device thrombosis control, in vitro modelling, medical device materials including ePTFE, hydrogels and genetically engineered biomaterials.
Frederic Field, Director of Development
Mr. Field has 25+ years of medical device product development experience in a variety of start-up companies bringing to market drug delivery infusion pumps, injection needle safety devices, and minimally invasive surgical instruments. His involvement has spanned proof of concept and initial prototype development, verification, validation, and commercial release of the products. He has actively participated in product user studies both in the U.S. and Europe and been directly involved with most of the regulatory submissions for these products. He is an experienced manager in start-up environments. Prior to joining 3DT, he was VP of Research and Development at Safety Syringes, Inc., until it was acquired by Becton Dickinson. Mr. Field earned a BS in Bioengineering and an MS in Applied Mechanics at UC, San Diego.
Mengjun Wang, MD, MS Chief Physiologist
Dr. Mengjun Wang has 10+ years of experiences in in-vivo efficacy/safety studies of cardiovascular devices/pharmaceuticals. Prior to joining the 3DT Holdings, LLC, he worked at the Henry Ford Heart & Vascular Institute, MI for 12 years. His work fully focused on understanding the pathophysiology of heart failure, and the development and testing of novel therapeutic modalities for the treatment and prevention of heart failure and other cardiovascular diseases. He has extensive hands-on experiences in pre-clinical cardiovascular device studies with large animals and strong expertise in performing cardiovascular interventions/surgery. Dr. Wang obtained his MD and MS degrees from Hebei Medical University and Peking University in China and was a highly trained surgeon before moving to the USA. He received research training at Peking University, Creighton University and University of North Carolina at Chapel Hill. He also earned a MS degree in the Medical Informatics from the University of Nebraska at Omaha.
Babacar Diouf, QA/Regulatory Affairs Manager
Babacar brings over 22 years of Engineering, Quality Engineering, Regulatory Affairs, and Quality Management Systems experience at 3DT Holdings. A native of Senegal, Babacar speaks four languages to go along with his Geological Engineering degree from the Institute of Earth Science; Cheikh Anta Diop University of Dakar, Senegal. Before joining the 3DT team, Babacar worked in the mining industry in Africa as a field geologist with a focus in geochemical exploration for gold and base metals. He spent four years in quality assurance in automotivesafety products, and 14 years in the medical device industry including ten years as an executive in regulatory affairs and quality systems.
Babacar is a senior member of the American Society for Quality (ASQ) and a member of the Regulatory Affairs Professionals Society (RAPS).
Babacar is a certified ISO13485:2016 Auditor, a certified MDSAP model auditor, an ASQ Certified Quality Auditor, and an ASQ Certified Quality Engineer.
Babacar holds a Master’s degree in Executive Leadership and Organizational Change from Northern Kentucky University.”
Alex Lillo, Office Manager
Accomplished professional banker with more than 20 years of building strategic client relationships, during which he managed several Bank and Credit Union branches. As Sr. International Private Banking, maximized the profitability of a portfolio consisting of 230 high net worth clients with 40 Million in deposits and 10 Million in loan balances. Also, spearheaded the company’s new BSA policies and procedures across our wealth management accounts within a 3 month deadline, and avoid possible FDIC Regulators orders of consent and/or fines, while passing several internal audits. Bilingual in English and Spanish, with a Bachelor of Science Degree in Business Administration (Finance), San Diego State University.